Iranian Knowledge-Based Firm Produces Transplant Tissues from Human Body
“These transplant tissues, which are often prepared from the bones of the human body, are widely used in orthopedic, neurological and dental surgeries,” Elham Majidinia, the representative of the marketing and production team of the knowledge-based company, told ANA.
Noting that heart valves are one of the most widely used products of the company, she said, “Heart valves with different diameters for adults and children are among the most widely used knowledge-based products of the company, which are currently applied, specially in Shahid Rajayee hospital and children's medical centers.”
“At present, there are only two types of heart valves for transplantation in children's bodies; synthetic material and animal fibers. Heart valves with human tissue are rarely produced by two companies in Iran,” Majidinia said.
“One of the most important applications of human transplant tissues is in the field of bone tumor treatment. In this process, the patient's bone is drained and the allograft tissue is placed in the human body instead,” she added.
Majidinia explained that at present only two Iranian companies, one in Tehran and the other on the Kish Island, produce human tissue allografts in the Middle East region.
In a relevant development in February, Iranian researchers had also succeeded in making a technological device that is capable to concurrently decellularize and cellularize the transplanted tissue, and prevents graft rejection and side effects of immunosuppressive drugs.
“The device we have developed helps to remove cells from the graft tissue scaffold using a series of laboratory solutions and materials. We can also give it a cell-free scaffold to add new cells,” Seyed Mohammad Amin Haramshahi, a faculty member of Iran University of Medical Sciences, told ANA.
Noting that the device helps the researcher to prepare the ground for making high-quality products with few complications, he said, “The challenge we face in preparation of transplanted tissue is that the products that are made at different times of decellularization are not the same because they depend on the user; but by using the device, this challenge is resolved and the settings of the device can be saved and the process can be repeated based on the same previous setting.”
Haramshahi explained that the time of product manufacturing process has shortened with this device, saying, “Similar devices in the market do not perform both decellularization and cellularization at the same time. Also, the possibility of remote control, like turning off the device at the end of the process or changing the intensity of the solution flow, is one of the important features of this technology and distinguishes it from other devices.”
4155/v
