Improving Healing Rate of Bone Injuries with Iran-Made Technological design
“Using scaffolds as a suitable ground for the proliferation and growth of cells and tissues can help continued cell growth until the complete replacement of the spot by the host tissue,” said Abouzar Rezayee Barvati, a Ph.D. student in metallurgical and materials engineering at Islamic Azad University’s Najafabad branch.
Noting that various methods exist for making three-dimensional metal scaffolds for use in bone tissue engineering, he said, “One of the suitable methods for producing metal scaffolds is the casting method, which was used in this research. In this method, molten magnesium is cast in a special mold containing space-creating materials, and a magnesium scaffold is finally produced after removing the space-creating materials.”
“This method is very suitable in terms of uniformity of physical and mechanical properties and the cost of scaffolding, and it can be mass-produced and industrialized,” Rezayee Barvati said.
Critical sized bone defects have to be filled with material to allow bone healing. The golden standard for this treatment is autogenous bone grafting. Because of donor size morbidity, equivalent synthetic bone scaffolds should be developed. Different materials, specially ceramics and polymers, are in the focus. Calcium phosphate ceramics show similar properties to bone and are degradable. Different modifications can improve the bioactive features.
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