Iranian Company Produces Smart Pharmaceutical Nanocarrier
The new supermagnetic intelligent nanocarrier is a polymer capsule that can contain special drugs, particularly anticancer medicine, and release them only in the cancerous tissue.
“The smart pharmaceutical nanocarrier product, if used in industrial production, specially in the field of anticancer drugs, can be a very good and useful treatment for patients who are suffering from this disease,” Hossein Peyman, the managing director of the knowledge-based ‘Pouyesh Pajouhan Asou’ company and a faculty member of the Islamic Azad University’s Ilam branch, told ANA.
The advantage of the supermagnetic intelligent drug carrier is that by taking anticancer drugs, such drugs will not have a harmful and destructive impact on other body tissues.
In a relevant development in January, Iranian researchers at the University of Tabriz had also succeeded in identifying and preparing a new drug delivery system with the help of nanotechnology based on polysaccharides or covalent organic frameworks for targeted delivery of drugs to cancer cells.
“Direct prescription of anticancer drugs can cause many side effects due to accumulation in non-target organs, tissues or cells. Also, anticancer drug molecules have limitations like low stability, low targeting efficiency, low permeability, and uncontrolled drug release,” said Hassan Namazi, a PhD student in organic polymer chemistry at Dalhousie University in Canada and a professor at the University of Tabriz.
Noting that in recent years, new drug carrier systems, specially carriers based on porous nanoparticles with high loading capacity and controlled drug release, have largely resolved problems and restrictions, he said, “Covalent organic frameworks are the most remarkable emerging porous organic materials due to their unique properties.”
“In this research project, covalent organic frameworks with immune bonds obtained as a result of the reaction of different aldehydes and amines were used on a substrate of nanoparticles or polysaccharides which can be used for targeted delivery of drugs to cancer cells,” Namazi said.
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