Iranian Scientists Indigenize Quantitative Phase Imaging Microscope

Iranian Scientists Indigenize Quantitative Phase Imaging Microscope

TEHRAN (ANA)- Iranian researchers succeeded in designing and building a Quantitative Phase Imaging (QPI) microscope which provides both quantitative and beautiful images of living cells.
News ID : 6565

In this research, a QPI accessory has been proposed which can be installed on conventional optical microscopes and equip them with a tool for digital holographic microscopy.

The proposed part includes a double Fresnel prism with a certain vertex angle, which can form an interference frieze if the coherent light of the laser is guided inside the microscope. A digital detector is placed at the end part of the piece to record full monographs.

By installing this part on any type of optical microscope, the scientists can have a very stable digital whole-view microscope device which provides the possibility of imaging, studying and characterizing living cells without the need to use anti-vibration optical tables.

The proposed device enjoys a very high efficiency in 3D imaging of transparent samples, specially biological samples, and quantitative analysis of their dynamics, and it can be easily used for quantitative study of cell dynamics in medical and biological research, 3D surface topography, testing and characterization of various structures in science, microelectromechanical materials and systems, measurement of changes in refractive index of fluids in microchannels, study of nonlinear phenomena and many other research and industrial applications.

In a relevant development in December, Iranian researchers at Shahid Beheshti University had also managed to design and produce advanced Raman microscope used for identification of molecules and studying chemical bonds.

“Among the most important achievements of Shahid Beheshti University, I can mention the advanced Raman microscope,” Qassem Qassemi, a representative of Shahid Beheshti University's Research Department, told ANA.

“Raman microscope is a spectroscopic device capable of spectroscopic measurement of areas with micron dimensions,” he explained.

“It is a laser-based spectroscopy system used to perform Raman spectroscopy. The Raman spectroscopy method is a precise method for identifying and characterizing a wide range of materials, and we have managed to indigenize it based on detailed research,” Qassemi said.

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