Visual Identification of Impurities in Liquid Drugs Possible via Using Iran-Made Kit

Mojtaba Seyedi, one of the researchers of the project, said that the kit which is mainly used by drug production plants has thus far been procured via import.

He further added that identification of pharmaceutical impurities in the drug development process had been actually aimed to fully show the chemical structures of unknown pharmaceutical impurities present in either drug substances or drug products above a particular threshold.

The researcher went on to say that the impurity present in a drug can affect its quality and thus its efficiency, it is, therefore, crucial to know about impurities.

Seyedi said that it is very important for drug manufacturers to know whether any impurities have entered the glass vials during the drug development process.

He underscored that the produced drug must be free of any impurities. In the process of drug production, some impurities may enter the drugs in the form of liquid or solid, but the identification of these impurities is very important for manufacturers.

Seyedi said that a simple way to find solid impurities in the drug is to examine it using a magnifying glass or by placing the vials in front of a light source. Of course such a way can make problem for the eyes.

"For this purpose, the designed kit, in addition to magnification, shines a light from the back of the vial, which illuminates only a part of the light that passes through the vial," he added.

"The kit was designed and built based on the polarization technique that will let only the light that shines through the glass vial pass," the researcher said, adding, "This will cause the suspended particles in the drug to be observed more quickly."

Seyedi added that if the kit is used in the production line, it will be possible to identify drug impurities by installing a mechanical rail.

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