Iranian Knowledge-Based Firm Develops Atomic Force Microscope for Biological Studies
“The new product of this company, an Atomic Force Microscope, is utilized for conducting studies on biological samples, living tissue and cells,” said Masoumeh Nasseri, one of the researchers of the knowledge-based company.
“The microscope is used to examine the surface of biological samples, but its difference with other AFMs is that researchers are able to take images of the tissue of the sample in liquid environments,” she added.
Nasseri explained that generally, in biological works, a series of tissues should be in a buffer environment so that the tissue remains intact, or in some cases, it is necessary to examine the tissues live, adding that this device allows us to take images of the tissues in the buffer environment and drying the sample is not necessary.
“In addition, this microscope provides researchers with the possibility of imaging the bottom surface of the sample. Once the sample is placed on the slide, it can also be imaged underneath, which is very important in biological studies,” she stated.
Atomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure surface roughness. AFM is a kind of scanning probe microscope, and its near-field technique is based on the interaction between a sharp tip and the atoms of the sample surface.
In the past decade, the AFM has emerged as a powerful tool to obtain the nanostructural details and biomechanical properties of biological samples, including biomolecules and cells.
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