Researchers Develop Biodegradable Material for Enhanced Wound Healing, Skin Regeneration
The study, jointly conducted by the Zhongnan Hospital of Wuhan University and the Wuhan University of Technology, has been published in the International Journal of Biological Macromolecules.
The biocomposite material is made from silk fibroin, sodium alginate and other natural polymers. When applied to a wound, its micro-nano layered structure guides skin cells to "climb" to various skin layers, promoting full-thickness skin repair and regeneration, according to Wang Xinyu, a professor at the Wuhan University of Technology.
This process results in the growth of native-like skin, which differs from artificial skin and possesses normal sensory functions like touch and pain perception.
This material can be absorbed by the human body or excreted as metabolic byproducts such as amino acids, carbon dioxide and water.
This breakthrough can be applied in the repair of skin and mucosal defects in the oral and maxillofacial regions, as well as the repair of burn-induced skin defects.
It can accelerate wound healing and address issues such as a shortage of autologous skin graft materials and non-degradable repair materials, as well as allergies.
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