Iranian Researchers Make Smart Coating to Prevent Moisture from Entering Tablet
“Our product creates a coating on the tablet and makes it easier to swallow and omits the unpleasant taste of the tablet,” Akram Seifi, a representative of the knowledge-based company, told ANA.
“This coating also has specialized applications. It is important if the physician wants the tablet to open in the stomach or intestine. The active ingredient of some tablets is sensitive to moisture and therefore, this polymer coating prevents moisture from entering the tablet,” she added.
“The coating is actually a powder and the polymers used in the powder on the tablet are different based on their function. Various polymers are used to open the tablet in the stomach and intestines. HPMC polymer, for instance, opens in the stomach. This HPMC is actually a chemically-modified cellulose polymer that is harmless to humans,” Seifi said.
She explained that the EUDRAGIT polymer existing in the coating powder leads to disintegration of the tablet in the intestine, adding that the pill has also been made smart based on the coating material and opens in the intestine or stomach as needed.
EUDRAGIT polymers are neutral in taste and smell, to help mask the bitterness of certain APIs or other unpleasant odors.
To improve drug swallowability, they enable smooth, glossy surfaces for a pleasant feel in the mouth and are highly effective in coatings as thin as 10 to 20 μm.
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